— InSilico Medicine\uacfc\u00a0\uc7a0\uc7ac\uc801\u00a0\uc720\ubc29\uc554\u00a0\uce58\ub8cc\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\uc554\u00a0\uc801\uc751\uc99d\uc5d0\u00a0\ub300\ud55c\u00a0\uc0c8\ub85c\uc6b4\u00a0KAT6 \uc5b5\uc81c\uc81c\uc758\u00a0\uc804\u00a0\uc138\uacc4\u00a0\ub3c5\uc810\uc801\u00a0\ub77c\uc774\uc120\uc2a4\u00a0\uacc4\uc57d\u00a0\uc131\uc0ac<\/p>\n
KAT6\uc740 \ud638\ub974\ubaac \ubbfc\uac10\uc131 \uc720\ubc29\uc554 \ubc0f \uae30\ud0c0 \uc554\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \ud45c\uc801\uc774\ub2e4. KAT6A\/B \uacfc\ub2e4\ubc1c\ud604\uc740 \uac00\uc7a5 \ud754\ud55c \ud558\uc704 \uc720\ud615\uc778 ER+\/HER2- \uc720\ubc29\uc554 \ud658\uc790\uc758 \ubd88\ub7c9\ud55c \uc784\uc0c1 \uc608\ud6c4\uc640 \uc0c1\uad00\uad00\uacc4\uac00 \uc788\ub2e4. \uc774 \ubd84\uc790\ub294 \uac15\ub825\ud55c \uc804\uc784\uc0c1 \ud65c\uc131\uc744 \uc785\uc99d\ud588\ub2e4. InSilico\ub294 12\uc6d4 \ucd08 San Antonio Breast Cancer Symposium\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \ubd84\uc790\uc5d0 \ub300\ud55c \ub370\uc774\ud130\ub97c \ubc1c\ud45c\ud588\ub2e4. \uc774 \uacc4\uc57d\uc740 \uc120\uc9c0\uae09\uacfc \ub9c8\uc77c\uc2a4\ud1a4 \uc9c0\uae09\uc744 \ud3ec\ud568\ud558\uace0 \uc7a0\uc7ac\uc801 \ubcf5\ud569 \uac00\uce58\uac00 5\uc5b5 \ubd88 \uc774\uc0c1\uc774\uba70 \ud310\ub9e4 \ub85c\uc5f4\ud2f0\uac00 \uc788\ub2e4. <\/p>\n
\uc774\ud0c8\ub9ac\uc544\u00a0\ud53c\ub80c\uccb4, \ubbf8\uad6d\u00a0\ub274\uc695\u00a02024\ub144\u00a01\uc6d4\u00a05\uc77c\u00a0\/PRNewswire=\uc5f0\ud569\ub274\uc2a4\/ — \uc120\ub3c4\uc801\uc778\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc81c\uc57d\u00a0\ubc0f\u00a0\uc9c4\ub2e8\u00a0\ud68c\uc0ac\uc778\u00a0Menarini Group\uacfc\u00a0Menarini Group\uc758\u00a0\uc644\uc804\u00a0\uc18c\uc720\u00a0\uc790\ud68c\uc0ac\ub85c\u00a0\uc554\u00a0\ud658\uc790\uc5d0\uac8c\u00a0\uc804\ud658\uc801\u00a0\uc554\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\uc81c\uacf5\ud558\ub294\u00a0\ub370\u00a0\uc911\uc810\uc744\u00a0\ub450\ub294\u00a0Stemline Therapeutics, Inc.,\ub294\u00a0\uc624\ub298\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\uc758\u00a0\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5(AI)\uc5d0\u00a0\uae30\ubc18\ud55c\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\ud68c\uc0ac\uc778\u00a0InSilico Medicine\uacfc\u00a0\ud568\uaed8\u00a0\ud638\ub974\ubaac\u00a0\ubbfc\uac10\uc131\u00a0\uc554\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\uc885\uc591\ud559\u00a0\uc801\uc751\uc99d\uc5d0\u00a0\ub300\ud55c\u00a0\uc7a0\uc7ac\uc801\u00a0\uce58\ub8cc\uc81c\ub85c\uc11c\u00a0InSilico\uc758\u00a0AI \ud50c\ub7ab\ud3fc\uc744\u00a0\uc0ac\uc6a9\ud574\u00a0\uc124\uacc4\ud55c\u00a0\uc0c8\ub85c\uc6b4\u00a0\uc18c\ubd84\uc790\u00a0KAT6A \uc5b5\uc81c\uc81c\ub97c\u00a0\uac1c\ubc1c\ud558\uace0\u00a0\uc0c1\uc6a9\ud654\ud558\ub294\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uad8c\ud55c\uc744\u00a0Stemline\uc5d0\u00a0\ubd80\uc5ec\ud558\ub294\u00a0\ub3c5\uc810\uc801\u00a0\ub77c\uc774\uc120\uc2a4\u00a0\uacc4\uc57d\uc744\u00a0\uccb4\uacb0\ud588\ub2e4\uace0\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n
\uc720\ubc29\uc554\uc740\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc5ec\uc131\uc5d0\uc11c\u00a0\uac00\uc7a5\u00a0\ud754\ud558\uac8c\u00a0\uc9c4\ub2e8\ub418\ub294\u00a0\uc885\uc591\u00a0\uc720\ud615\uc73c\ub85c\u00a0\uc8fc\uc694\u00a0\uc554\u00a0\uc0ac\ub9dd\u00a0\uc6d0\uc778\uc774\ub2e4.1\u00a0\uc720\ubc29\uc554\uc758\u00a0\uc57d\u00a070%\ub294\u00a0\uc5d0\uc2a4\ud2b8\ub85c\uac90\u00a0\uc218\uc6a9\uccb4\u00a0\uc591\uc131(ER+)\uc774\uba70\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc774\u00a0\uc5ec\uc804\ud788\u00a0ER+ \uc720\ubc29\uc554\u00a0\ud658\uc790\uc758\u00a0\uae30\ubcf8\u00a0\uc694\ubc95\uc774\ub2e4. \ud558\uc9c0\ub9cc, \uc885\uc591\uc774\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc5d0\u00a0\ub0b4\uc131\uc744\u00a0\ubcf4\uc77c\u00a0\uc218\u00a0\uc788\uc5b4\u00a0\uc9c8\ubcd1\u00a0\uc9c4\ud589\uc774\u00a0\ub098\ud0c0\ub0a0\u00a0\uc218\u00a0\uc788\ub2e4. \uc774\ub294\u00a0\uc720\uc758\ud55c\u00a0\uc784\uc0c1\uc801\u00a0\ubb38\uc81c\ub85c\u00a0\uce58\ub8cc\u00a0\ub0b4\uc131\uc744\u00a0\uadf9\ubcf5\ud558\ub294\u00a0\ub370\u00a0\ub3c4\uc6c0\uc774\u00a0\ub418\ub294\u00a0\uc0c8\ub85c\uc6b4\u00a0\uce58\ub8cc\ubc95\uc5d0\u00a0\ub300\ud55c\u00a0\uae34\uae09\ud55c\u00a0\ud544\uc694\uc131\uc744\u00a0\uac15\uc870\ud55c\ub2e4.<\/p>\n
KAT6A\uc740\u00a0\uba87\uba87\u00a0\uc554\uc5d0\uc11c\u00a0\uc911\uc694\ud55c\u00a0\uc5ed\ud560\uc744\u00a0\ud558\ub294\u00a0\uac83\uc73c\ub85c\u00a0\uc54c\ub824\uc838\u00a0\uc788\ub2e4. KAT6A \uacfc\ub2e4\ubc1c\ud604\uc740\u00a0\uc720\ubc29\uc554\uc5d0\uc11c\u00a0\uac00\uc7a5\u00a0\ud754\ud55c\u00a0\ud558\uc704\u00a0\uc720\ud615\uc778\u00a0ER+\/HER2- \uc720\ubc29\uc554\u00a0\ud658\uc790\uc5d0\uc11c\u00a0\ubd88\ub7c9\ud55c\u00a0\uc784\uc0c1\u00a0\uc608\ud6c4\uc640\u00a0\uc0c1\uad00\uad00\uacc4\uac00\u00a0\uc788\ub2e4. \uc804\uc784\uc0c1\u00a0\uc2dc\ud5d8\uc5d0\uc11c\u00a0\uc774\u00a0\ubd84\uc790\ub294\u00a0\uc5ec\ub7ec\u00a0CDX \ubc0f\u00a0PDX \ubaa8\ub378\uc5d0\uc11c\u00a0KAT6A\uc5d0\u00a0\ub300\ud574\u00a0\uac15\ub825\ud55c\u00a0\uc5b5\uc81c\ub97c\u00a0\uc785\uc99d\ud588\uc73c\uba70\u00a0\uc6b0\uc218\ud55c\u00a0\uc720\ud6a8\uc131\uacfc\u00a0\uc548\uc804\uc131\uc744\u00a0\ubcf4\uc600\ub2e4. InSilico\ub294\u00a012\uc6d4\u00a0\ucd08\u00a0San Antonio Breast Cancer Symposium\uc5d0\uc11c\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubd84\uc790\uc5d0\u00a0\ub300\ud55c\u00a0\ub370\uc774\ud130\ub97c\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n
Menarini Group CEO\uc778\u00a0Elcin Barker Ergun\uc740\u00a0“\uc720\ub9dd\ud55c\u00a0\uc0c8\ub85c\uc6b4\u00a0\uce58\ub8cc\u00a0\uc811\uadfc\ubc95\uc744\u00a0\ud0d0\uc0c9\ud558\uace0\u00a0\uc804\ud658\uc801\uc778\u00a0\uc0c8\ub85c\uc6b4\u00a0\ud56d\uc554\u00a0\uc694\ubc95\uc744\u00a0\ubc1d\ud600\ub0b4\uae30\u00a0\uc704\ud574\u00a0\uc774\u00a0\ubd84\uc57c\uc758\u00a0\ub9ac\ub354\ub85c\u00a0\uc0dd\uc131\ud615\u00a0AI\ub97c\u00a0\uac16\ucd98\u00a0InSilico\uc640\u00a0\ud611\ub825\ud558\uac8c\u00a0\ub418\uc5b4\u00a0\uae30\uc058\ub2e4”\uba70\u00a0“\ubbf8\uad6d\uacfc\u00a0\uc720\ub7fd\uc5d0\uc11c\u00a0\uadfc\u00a020\ub144\uc774\u00a0\uc9c0\ub098\u00a0ER+, HER2- \uc720\ubc29\uc554\u00a0\ud658\uc790\ub97c\u00a0\uc704\ud55c\u00a0elacestrant\ub85c\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc5d0\u00a0\ucd5c\ucd08\uc758\u00a0\ud601\uc2e0\uc744\u00a0\uc81c\uacf5\ud55c\u00a0\ubcf8\uc0ac\uc758\u00a0\ubaa9\ud45c\ub294\u00a0\ud658\uc790\ub4e4\uc758\u00a0\uc608\ud6c4\ub97c\u00a0\ub354\uc6b1\u00a0\uc99d\uac15\ud558\ub294\u00a0\uac83\uc73c\ub85c\u00a0KAT6A\ub97c\u00a0\ud45c\uc801\ud558\ub294\u00a0\uac83\uc744\u00a0\ud1b5\ud574\u00a0\uc720\ubc29\uc554\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\uc9c8\ubcd1\uc5d0\uc11c\u00a0\uac00\ub2a5\ud560\u00a0\uac83”\uc774\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n
\uc774\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubd84\uc790\ub294\u00a0InSilico R&D \ud300\uc5d0\uc11c\u00a0\uc774\ub4e4\uc758\u00a0\uc5d4\ub4dc\ud22c\uc5d4\ub4dc(end-to-end) \uc81c\uc57d\u00a0\uc0dd\uc131\ud615\u00a0AI \ud50c\ub7ab\ud3fc\uc744\u00a0\uc0ac\uc6a9\ud574\u00a0KAT6A\ub97c\u00a0\uc5b5\uc81c\ud558\uace0\u00a0\uc804\uc0ac\u00a0\uc218\uc900\uc5d0\uc11c\u00a0\ub0b4\ubd84\ube44\u00a0\uc218\uc6a9\uccb4(ER)\ub97c\u00a0\ucc28\ub2e8\ud558\ub3c4\ub85d\u00a0\ub9cc\ub4e4\uc5b4\uc838\u00a0\ub3cc\uc5f0\ubcc0\uc774\u00a0\ub610\ub294\u00a0\ub9ac\uac04\ub4dc\u00a0\ube44\uc758\uc874\uc801\u00a0ER\uc758\u00a0\uad6c\uc870\uc801\u00a0\ud65c\uc131\ud654\ub85c\u00a0\uc778\ud55c\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\u00a0\ub0b4\uc131\uc744\u00a0\uadf9\ubcf5\ud560\u00a0\uc218\u00a0\uc788\ub294\u00a0\uc7a0\uc7ac\uc131\uc744\u00a0\uc81c\uacf5\ud55c\ub2e4. \ud604\uc7ac, CDK4\/6 \uc5b5\uc81c\uc81c\uc640\u00a0\ubcd1\uc6a9\ud55c\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc774\u00a0\uc9c4\ud589\uc131\u00a0\ub610\ub294\u00a0\uc804\uc774\uc131\u00a0\uc9c8\ubcd1\uc774\u00a0\uc788\ub294\u00a0ER+\/HER2- \uc720\ubc29\uc554\u00a0\ud658\uc790\uc758\u00a0\ud45c\uc900\u00a0\uce58\ub8cc\uc774\ub2e4. \uc608\ud6c4\ub97c\u00a0\ub354\uc6b1\u00a0\ud655\uc7a5\ud558\uae30\u00a0\uc704\ud574\u00a0CDK4\/6 \uc5b5\uc81c\uc81c\u00a0\ubc0f\/\ub610\ub294\u00a0\uc0c8\ub85c\uc6b4\u00a0\uacbd\uad6c\u00a0SERD\uc640\uc758\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubcd1\uc6a9\uc694\ubc95\uc774\u00a0\ud544\uc694\ud558\ub2e4.<\/p>\n
InSilico Medicine\uc758\u00a0\ucc3d\uc5c5\uc790\uc774\uc790\u00a0\uacf5\ub3d9\u00a0CEO\uc778\u00a0Alex Zhavoronkov \ubc15\uc0ac\ub294\u00a0“\ub2f9\uc0ac\uc758\u00a0\ucd5c\uc2e0\u00a0\uc0dd\uc131\ud615\u00a0AI\ub85c\u00a0\uace0\uc548\ub41c\u00a0\uc694\ubc95\uc774\u00a0\uc720\ubc29\uc554\u00a0\ud658\uc790\uc5d0\uac8c\u00a0\uc0c8\ub85c\uc6b4\u00a0\uc7a0\uc7ac\uc801\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\uc81c\uacf5\ud560\u00a0\uac00\ub2a5\uc131\uc774\u00a0\uc788\ub2e4\ub294\u00a0\ub370\u00a0\uc815\ub9d0\u00a0\uae30\uc058\ub2e4”\uba70\u00a0” Stemline\uc740\u00a0\ud601\uc2e0\uc801\uc778\u00a0\ube44\uc804\uc744\u00a0\uac00\uc9c0\uace0\u00a0\uc788\uace0\u00a0\uc885\uc591\ud559\uc5d0\uc11c\u00a0\uc804\ud658\uc801\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\uc81c\uacf5\ud558\ub294\u00a0\ub370\u00a0\ud070\u00a0\uc911\uc810\uc744\u00a0\ub450\uace0\u00a0\uc788\uc5b4\u00a0\uc774\u00a0\ubd84\uc790\ub97c\u00a0\uac1c\ubc1c\ud558\uace0\u00a0\uc784\uc0c1\uc2dc\ud5d8\uc744\u00a0\uc9c4\ud589\ud558\ub294\u00a0\ub370\u00a0\uc788\uc5b4\u00a0\uc774\uc0c1\uc801\uc778\u00a0\ud30c\ud2b8\ub108”\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n
\uc774\u00a0\uacc4\uc57d\u00a0\uc870\uac74\uc5d0\uc11c\u00a0Stemline\uc740\u00a0InSilico\uc5d0\u00a01200\ub9cc\u00a0\ubd88\uc744\u00a0\uc120\uc9c0\uae09\ud560\u00a0\uac83\uc774\ub2e4. \ubaa8\ub4e0\u00a0\uac1c\ubc1c, \uaddc\uc81c, \uc0c1\uc6a9\u00a0\ub9c8\uc77c\uc2a4\ud1a4\uc744\u00a0\ud3ec\ud568\ud558\uc5ec\u00a0\uc774\u00a0\uac70\ub798\uc758\u00a0\ubcf5\ud569\u00a0\uac00\uce58\ub294\u00a05\uc5b5\u00a0\ubd88\u00a0\uc774\uc0c1\uc774\uba70\u00a0\ub85c\uc5f4\ud2f0\ub294\u00a0\ub450\u00a0\uc790\ub9bf\uc218\uc5d0\u00a0\ub2ec\ud55c\ub2e4.<\/p>\n
Menarini Group\uc5d0\u00a0\ub300\ud574\u00a0<\/p>\n
Menarini Group\uc740 \ub9e4\ucd9c\uc774 44\uc5b5 \ub2ec\ub7ec \uc774\uc0c1\uc774\uace0 17,000\uba85\uc774 \ub118\ub294 \uc9c1\uc6d0\uc744 \ub454 \uc120\ub3c4\uc801\uc778 \uad6d\uc81c \uc81c\uc57d \ubc0f \uc9c4\ub2e8 \ud68c\uc0ac\uc774\ub2e4. Menarini\ub294 \uc2ec\uc7a5\ud559, \uc885\uc591\ud559, \ud638\ud761\uae30\ud559, \uc18c\ud654\uae30\ud559, \uac10\uc5fc \uc9c8\ud658, \ub2f9\ub1e8\ubcd1, \uc5fc\uc99d \ubc0f \uc9c4\ud1b5 \uc758\uc57d\ud488\uc73c\ub85c \ubd80\ud569\ub418\uc9c0 \uc54a\ub294 \uc218\uc694\uac00 \ub192\uc740 \uce58\ub8cc \uc601\uc5ed\uc5d0 \uc911\uc810\uc744 \ub454\ub2e4. 18\uac1c \uc81c\uc870\uc18c\uc640 9\uac1c \uc5f0\uad6c\uac1c\ubc1c \uc13c\ud130\uac00 \uc788\ub294 Menarini Group\uc758 \uc758\uc57d\ud488\uc740 \uc804 \uc138\uacc4 140\uac1c\uad6d\uc5d0 \uc81c\uacf5\ub41c\ub2e4. \ucd94\uac00 \uc815\ubcf4\ub294 menarini.com\uc744 \ucc38\uc870\ud55c\ub2e4.<\/p>\n
Stemline Therapeutics, Inc.,\uc5d0\u00a0\ub300\ud574<\/p>\n
Stemline Therapeutics, Inc.,\uc740 Menarini Group\uc758 \uc644\uc804 \uc18c\uc720 \uc790\ud68c\uc0ac\ub85c \uc0c8\ub85c\uc6b4 \uc554 \uce58\ub8cc\uc81c\uc758 \uac1c\ubc1c \ubc0f \uc0c1\uc6a9\ud654\uc5d0 \uc911\uc810\uc744 \ub454 \uc0c1\uc6a9 \ub2e8\uacc4 \uc0dd\ubb3c\uc758\uc57d\ud488 \ud68c\uc0ac\uc774\ub2e4. Stemline\uc740 \ubbf8\uad6d\uacfc \uc720\ub7fd \uc5f0\ud569\uc5d0\uc11c \ud558\ub098 \uc774\uc0c1\uc758 \ub0b4\ubd84\ube44 \uc694\ubc95 \ud6c4 \uc9c8\ubcd1 \uc9c4\ud589\uc744 \ubcf4\uc778 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uc6a9\uccb4(ER) \uc591\uc131, \uc778\uac04 \uc0c1\ud53c\uc131\uc7a5\uc778\uc790 \uc218\uc6a9\uccb4 1(HER2) \uc74c\uc131, ESR1 \ub3cc\uc5f0\ubcc0\uc774 \uc9c4\ud589\uc131 \ub610\ub294 \uc804\uc774\uc131 \uc720\ubc29\uc554\uc774 \uc788\ub294 \ud3d0\uacbd \ud6c4 \uc5ec\uc131 \ub610\ub294 \uc131\uc778 \ub0a8\uc131\uc758 \uce58\ub8cc\uc5d0 \uc801\uc751\ub418\ub294 \uacbd\uad6c \ub0b4\ubd84\ube44 \uc694\ubc95\uc778 ORSERDU\u00ae(elacestrant)\ub97c \uc2dc\ud310\ud558\uace0 \uc788\ub2e4. Stemline\uc740 \uacf5\uaca9\uc801 \ud608\uc561\uc554\uc778 \ubaa8\uad6c \ud615\uc9c8\uc138\ud3ec\uc591 \uc218\uc9c0\uc138\ud3ec \uc885\uc591(BPDCN) \ud658\uc790\uc5d0\uc11c CD123\uc744 \ud45c\uc801\ud558\ub294 \uc0c8\ub85c\uc6b4 \ud45c\uc801 \uce58\ub8cc\uc81c\uc778 ELZONRIS\u00ae(\uc131\ubd84\uba85: tagraxofusp-erzs)\ub3c4 \ubbf8\uad6d\uacfc \uc720\ub7fd\uc5d0\uc11c \ud310\ub9e4\ud558\uace0 \uc788\ub2e4. \uc774\ub294 \ud604\uc7ac\uae4c\uc9c0 \ubbf8\uad6d\uacfc \uc720\ub7fd\uc5f0\ud569\uc5d0\uc11cBPDCN\uc5d0 \ub300\ud574 \uc2b9\uc778\ub41c \uc720\uc77c\ud55c \uce58\ub8cc\uc81c\uc774\ub2e4. Stemline\uc740 \ub2e4\ubc1c\uc131 \uace8\uc218\uc885\uc5d0 \ub300\ud55c XPO1 \uc5b5\uc81c\uc81c\uc778 NEXPOVIO\u00ae(\uc131\ubd84\uba85: Selinexor)\ub3c4 \uc720\ub7fd\uc5d0\uc11c \ud310\ub9e4\ud558\uace0 \uc788\ub2e4. Stemline\uc740 \uc5ec\ub7ec \uace0\ud615\uc554 \ubc0f \ud608\uc561\uc554\uc5d0 \ub300\ud574 \uc5ec\ub7ec \ub2e8\uacc4\ub85c \uac1c\ubc1c\ub418\uace0 \uc788\ub294 \uad11\ubc94\uc704\ud55c \uc18c\ubd84\uc790 \ubc0f \uc0dd\ubb3c\ud559\uc801 \uc758\uc57d\ud488 \uc784\uc0c1 \ud30c\uc774\ud504\ub77c\uc778\ub3c4 \ubcf4\uc720\ud558\uace0 \uc788\ub2e4.<\/p>\n
InSilico Medicine\uc5d0\u00a0\ub300\ud574<\/p>\n
InSilico Medicine\uc740\u00a0\uc0dd\uc131\ud615\u00a0AI\ub97c\u00a0\uac16\ucd98\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\ud68c\uc0ac\ub85c\u00a0\ucc28\uc138\ub300\u00a0AI \uc2dc\uc2a4\ud15c\uc744\u00a0\uc0ac\uc6a9\ud574\u00a0\uc0dd\ubb3c\ud559, \ud654\ud559, \uc784\uc0c1\uc2dc\ud5d8\uc744\u00a0\uc5f0\uacb0\ud55c\ub2e4. \uc774\u00a0\ud68c\uc0ac\ub294\u00a0\uc0c8\ub85c\uc6b4\u00a0\ud45c\uc801\uc744\u00a0\ubc1c\uacac\ud558\uace0\u00a0\uc6d0\ud558\ub294\u00a0\uc18d\uc131\uc758\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubd84\uc790\u00a0\uad6c\uc870\ub97c\u00a0\uc0dd\uc131\ud558\uae30\u00a0\uc704\ud574\u00a0\ub525\u00a0\uc0dd\uc131\u00a0\ubaa8\ub378, \uac15\ud654\u00a0\ud559\uc2b5, \ubcc0\ud658\uae30\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\ud604\ub300\uc2dd\u00a0\uba38\uc2e0\u00a0\ub7ec\ub2dd\u00a0\uae30\uc220\uc744\u00a0\uc774\uc6a9\ud558\ub294\u00a0AI \ud50c\ub7ab\ud3fc\uc744\u00a0\uac1c\ubc1c\ud588\ub2e4. InSilico Medicine\uc740\u00a0\uc554, \uc12c\uc720\uc99d, \uba74\uc5ed, \uc911\ucd94\uc2e0\uacbd\uacc4\u00a0\uc9c8\ud658, \uac10\uc5fc\u00a0\uc9c8\ud658, \uc790\uac00\uba74\uc5ed\u00a0\uc9c8\ud658\u00a0\ubc0f\u00a0\ub178\ud654\u00a0\uad00\ub828\u00a0\uc9c8\ud658\uc5d0\u00a0\ub300\ud55c\u00a0\ud601\uc2e0\uc801\uc778\u00a0\uc57d\ubb3c\uc744\u00a0\ubc1c\uacac\ud558\uace0\u00a0\uac1c\ubc1c\ud558\ub294\u00a0\ud68d\uae30\uc801\uc778\u00a0\uc194\ub8e8\uc158\uc744\u00a0\uac1c\ubc1c\ud558\uace0\u00a0\uc788\ub2e4. www.insilico.com<\/a><\/p>\n 1 Sung\u00a0H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021 Feb 4<\/span>. doi: 10.3322\/caac.21660. Epub ahead of print. PMID: 33538338.<\/p>","protected":false},"excerpt":{"rendered":" <\/p>\n — InSilico Medicine\uacfc\u00a0\uc7a0\uc7ac\uc801\u00a0\uc720\ubc29\uc554\u00a0\uce58\ub8cc\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\uc554\u00a0\uc801\uc751\uc99d\uc5d0\u00a0\ub300\ud55c\u00a0\uc0c8\ub85c\uc6b4\u00a0KAT6 \uc5b5\uc81c\uc81c\uc758\u00a0\uc804\u00a0\uc138\uacc4\u00a0\ub3c5\uc810\uc801\u00a0\ub77c\uc774\uc120\uc2a4\u00a0\uacc4\uc57d\u00a0\uc131\uc0ac<\/p>\n KAT6\uc740 \ud638\ub974\ubaac \ubbfc\uac10\uc131 \uc720\ubc29\uc554 \ubc0f \uae30\ud0c0 \uc554\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \ud45c\uc801\uc774\ub2e4. KAT6A\/B \uacfc\ub2e4\ubc1c\ud604\uc740 \uac00\uc7a5 \ud754\ud55c \ud558\uc704 \uc720\ud615\uc778 ER+\/HER2- \uc720\ubc29\uc554 \ud658\uc790\uc758 \ubd88\ub7c9\ud55c \uc784\uc0c1 \uc608\ud6c4\uc640 \uc0c1\uad00\uad00\uacc4\uac00 \uc788\ub2e4. \uc774 \ubd84\uc790\ub294 \uac15\ub825\ud55c \uc804\uc784\uc0c1 \ud65c\uc131\uc744 \uc785\uc99d\ud588\ub2e4. InSilico\ub294 12\uc6d4 \ucd08 San Antonio Breast Cancer Symposium\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \ubd84\uc790\uc5d0 \ub300\ud55c \ub370\uc774\ud130\ub97c \ubc1c\ud45c\ud588\ub2e4. \uc774 \uacc4\uc57d\uc740 \uc120\uc9c0\uae09\uacfc \ub9c8\uc77c\uc2a4\ud1a4 \uc9c0\uae09\uc744 \ud3ec\ud568\ud558\uace0 \uc7a0\uc7ac\uc801 \ubcf5\ud569 \uac00\uce58\uac00 5\uc5b5 \ubd88 \uc774\uc0c1\uc774\uba70 \ud310\ub9e4 \ub85c\uc5f4\ud2f0\uac00 \uc788\ub2e4. <\/p>\n \uc774\ud0c8\ub9ac\uc544\u00a0\ud53c\ub80c\uccb4, \ubbf8\uad6d\u00a0\ub274\uc695\u00a02024\ub144\u00a01\uc6d4\u00a05\uc77c\u00a0\/PRNewswire=\uc5f0\ud569\ub274\uc2a4\/ — \uc120\ub3c4\uc801\uc778\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc81c\uc57d\u00a0\ubc0f\u00a0\uc9c4\ub2e8\u00a0\ud68c\uc0ac\uc778\u00a0Menarini Group\uacfc\u00a0Menarini Group\uc758\u00a0\uc644\uc804\u00a0\uc18c\uc720\u00a0\uc790\ud68c\uc0ac\ub85c\u00a0\uc554\u00a0\ud658\uc790\uc5d0\uac8c\u00a0\uc804\ud658\uc801\u00a0\uc554\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\uc81c\uacf5\ud558\ub294\u00a0\ub370\u00a0\uc911\uc810\uc744\u00a0\ub450\ub294\u00a0Stemline Therapeutics, Inc.,\ub294\u00a0\uc624\ub298\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\uc758\u00a0\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5(AI)\uc5d0\u00a0\uae30\ubc18\ud55c\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\ud68c\uc0ac\uc778\u00a0InSilico Medicine\uacfc\u00a0\ud568\uaed8\u00a0\ud638\ub974\ubaac\u00a0\ubbfc\uac10\uc131\u00a0\uc554\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\uc885\uc591\ud559\u00a0\uc801\uc751\uc99d\uc5d0\u00a0\ub300\ud55c\u00a0\uc7a0\uc7ac\uc801\u00a0\uce58\ub8cc\uc81c\ub85c\uc11c\u00a0InSilico\uc758\u00a0AI \ud50c\ub7ab\ud3fc\uc744\u00a0\uc0ac\uc6a9\ud574\u00a0\uc124\uacc4\ud55c\u00a0\uc0c8\ub85c\uc6b4\u00a0\uc18c\ubd84\uc790\u00a0KAT6A \uc5b5\uc81c\uc81c\ub97c\u00a0\uac1c\ubc1c\ud558\uace0\u00a0\uc0c1\uc6a9\ud654\ud558\ub294\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uad8c\ud55c\uc744\u00a0Stemline\uc5d0\u00a0\ubd80\uc5ec\ud558\ub294\u00a0\ub3c5\uc810\uc801\u00a0\ub77c\uc774\uc120\uc2a4\u00a0\uacc4\uc57d\uc744\u00a0\uccb4\uacb0\ud588\ub2e4\uace0\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n \uc720\ubc29\uc554\uc740\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc5ec\uc131\uc5d0\uc11c\u00a0\uac00\uc7a5\u00a0\ud754\ud558\uac8c\u00a0\uc9c4\ub2e8\ub418\ub294\u00a0\uc885\uc591\u00a0\uc720\ud615\uc73c\ub85c\u00a0\uc8fc\uc694\u00a0\uc554\u00a0\uc0ac\ub9dd\u00a0\uc6d0\uc778\uc774\ub2e4.1\u00a0\uc720\ubc29\uc554\uc758\u00a0\uc57d\u00a070%\ub294\u00a0\uc5d0\uc2a4\ud2b8\ub85c\uac90\u00a0\uc218\uc6a9\uccb4\u00a0\uc591\uc131(ER+)\uc774\uba70\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc774\u00a0\uc5ec\uc804\ud788\u00a0ER+ \uc720\ubc29\uc554\u00a0\ud658\uc790\uc758\u00a0\uae30\ubcf8\u00a0\uc694\ubc95\uc774\ub2e4. \ud558\uc9c0\ub9cc, \uc885\uc591\uc774\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc5d0\u00a0\ub0b4\uc131\uc744\u00a0\ubcf4\uc77c\u00a0\uc218\u00a0\uc788\uc5b4\u00a0\uc9c8\ubcd1\u00a0\uc9c4\ud589\uc774\u00a0\ub098\ud0c0\ub0a0\u00a0\uc218\u00a0\uc788\ub2e4. \uc774\ub294\u00a0\uc720\uc758\ud55c\u00a0\uc784\uc0c1\uc801\u00a0\ubb38\uc81c\ub85c\u00a0\uce58\ub8cc\u00a0\ub0b4\uc131\uc744\u00a0\uadf9\ubcf5\ud558\ub294\u00a0\ub370\u00a0\ub3c4\uc6c0\uc774\u00a0\ub418\ub294\u00a0\uc0c8\ub85c\uc6b4\u00a0\uce58\ub8cc\ubc95\uc5d0\u00a0\ub300\ud55c\u00a0\uae34\uae09\ud55c\u00a0\ud544\uc694\uc131\uc744\u00a0\uac15\uc870\ud55c\ub2e4.<\/p>\n KAT6A\uc740\u00a0\uba87\uba87\u00a0\uc554\uc5d0\uc11c\u00a0\uc911\uc694\ud55c\u00a0\uc5ed\ud560\uc744\u00a0\ud558\ub294\u00a0\uac83\uc73c\ub85c\u00a0\uc54c\ub824\uc838\u00a0\uc788\ub2e4. KAT6A \uacfc\ub2e4\ubc1c\ud604\uc740\u00a0\uc720\ubc29\uc554\uc5d0\uc11c\u00a0\uac00\uc7a5\u00a0\ud754\ud55c\u00a0\ud558\uc704\u00a0\uc720\ud615\uc778\u00a0ER+\/HER2- \uc720\ubc29\uc554\u00a0\ud658\uc790\uc5d0\uc11c\u00a0\ubd88\ub7c9\ud55c\u00a0\uc784\uc0c1\u00a0\uc608\ud6c4\uc640\u00a0\uc0c1\uad00\uad00\uacc4\uac00\u00a0\uc788\ub2e4. \uc804\uc784\uc0c1\u00a0\uc2dc\ud5d8\uc5d0\uc11c\u00a0\uc774\u00a0\ubd84\uc790\ub294\u00a0\uc5ec\ub7ec\u00a0CDX \ubc0f\u00a0PDX \ubaa8\ub378\uc5d0\uc11c\u00a0KAT6A\uc5d0\u00a0\ub300\ud574\u00a0\uac15\ub825\ud55c\u00a0\uc5b5\uc81c\ub97c\u00a0\uc785\uc99d\ud588\uc73c\uba70\u00a0\uc6b0\uc218\ud55c\u00a0\uc720\ud6a8\uc131\uacfc\u00a0\uc548\uc804\uc131\uc744\u00a0\ubcf4\uc600\ub2e4. InSilico\ub294\u00a012\uc6d4\u00a0\ucd08\u00a0San Antonio Breast Cancer Symposium\uc5d0\uc11c\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubd84\uc790\uc5d0\u00a0\ub300\ud55c\u00a0\ub370\uc774\ud130\ub97c\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n Menarini Group CEO\uc778\u00a0Elcin Barker Ergun\uc740\u00a0“\uc720\ub9dd\ud55c\u00a0\uc0c8\ub85c\uc6b4\u00a0\uce58\ub8cc\u00a0\uc811\uadfc\ubc95\uc744\u00a0\ud0d0\uc0c9\ud558\uace0\u00a0\uc804\ud658\uc801\uc778\u00a0\uc0c8\ub85c\uc6b4\u00a0\ud56d\uc554\u00a0\uc694\ubc95\uc744\u00a0\ubc1d\ud600\ub0b4\uae30\u00a0\uc704\ud574\u00a0\uc774\u00a0\ubd84\uc57c\uc758\u00a0\ub9ac\ub354\ub85c\u00a0\uc0dd\uc131\ud615\u00a0AI\ub97c\u00a0\uac16\ucd98\u00a0InSilico\uc640\u00a0\ud611\ub825\ud558\uac8c\u00a0\ub418\uc5b4\u00a0\uae30\uc058\ub2e4”\uba70\u00a0“\ubbf8\uad6d\uacfc\u00a0\uc720\ub7fd\uc5d0\uc11c\u00a0\uadfc\u00a020\ub144\uc774\u00a0\uc9c0\ub098\u00a0ER+, HER2- \uc720\ubc29\uc554\u00a0\ud658\uc790\ub97c\u00a0\uc704\ud55c\u00a0elacestrant\ub85c\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc5d0\u00a0\ucd5c\ucd08\uc758\u00a0\ud601\uc2e0\uc744\u00a0\uc81c\uacf5\ud55c\u00a0\ubcf8\uc0ac\uc758\u00a0\ubaa9\ud45c\ub294\u00a0\ud658\uc790\ub4e4\uc758\u00a0\uc608\ud6c4\ub97c\u00a0\ub354\uc6b1\u00a0\uc99d\uac15\ud558\ub294\u00a0\uac83\uc73c\ub85c\u00a0KAT6A\ub97c\u00a0\ud45c\uc801\ud558\ub294\u00a0\uac83\uc744\u00a0\ud1b5\ud574\u00a0\uc720\ubc29\uc554\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\uc9c8\ubcd1\uc5d0\uc11c\u00a0\uac00\ub2a5\ud560\u00a0\uac83”\uc774\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n \uc774\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubd84\uc790\ub294\u00a0InSilico R&D \ud300\uc5d0\uc11c\u00a0\uc774\ub4e4\uc758\u00a0\uc5d4\ub4dc\ud22c\uc5d4\ub4dc(end-to-end) \uc81c\uc57d\u00a0\uc0dd\uc131\ud615\u00a0AI \ud50c\ub7ab\ud3fc\uc744\u00a0\uc0ac\uc6a9\ud574\u00a0KAT6A\ub97c\u00a0\uc5b5\uc81c\ud558\uace0\u00a0\uc804\uc0ac\u00a0\uc218\uc900\uc5d0\uc11c\u00a0\ub0b4\ubd84\ube44\u00a0\uc218\uc6a9\uccb4(ER)\ub97c\u00a0\ucc28\ub2e8\ud558\ub3c4\ub85d\u00a0\ub9cc\ub4e4\uc5b4\uc838\u00a0\ub3cc\uc5f0\ubcc0\uc774\u00a0\ub610\ub294\u00a0\ub9ac\uac04\ub4dc\u00a0\ube44\uc758\uc874\uc801\u00a0ER\uc758\u00a0\uad6c\uc870\uc801\u00a0\ud65c\uc131\ud654\ub85c\u00a0\uc778\ud55c\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\u00a0\ub0b4\uc131\uc744\u00a0\uadf9\ubcf5\ud560\u00a0\uc218\u00a0\uc788\ub294\u00a0\uc7a0\uc7ac\uc131\uc744\u00a0\uc81c\uacf5\ud55c\ub2e4. \ud604\uc7ac, CDK4\/6 \uc5b5\uc81c\uc81c\uc640\u00a0\ubcd1\uc6a9\ud55c\u00a0\ub0b4\ubd84\ube44\u00a0\uc694\ubc95\uc774\u00a0\uc9c4\ud589\uc131\u00a0\ub610\ub294\u00a0\uc804\uc774\uc131\u00a0\uc9c8\ubcd1\uc774\u00a0\uc788\ub294\u00a0ER+\/HER2- \uc720\ubc29\uc554\u00a0\ud658\uc790\uc758\u00a0\ud45c\uc900\u00a0\uce58\ub8cc\uc774\ub2e4. \uc608\ud6c4\ub97c\u00a0\ub354\uc6b1\u00a0\ud655\uc7a5\ud558\uae30\u00a0\uc704\ud574\u00a0CDK4\/6 \uc5b5\uc81c\uc81c\u00a0\ubc0f\/\ub610\ub294\u00a0\uc0c8\ub85c\uc6b4\u00a0\uacbd\uad6c\u00a0SERD\uc640\uc758\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubcd1\uc6a9\uc694\ubc95\uc774\u00a0\ud544\uc694\ud558\ub2e4.<\/p>\n InSilico Medicine\uc758\u00a0\ucc3d\uc5c5\uc790\uc774\uc790\u00a0\uacf5\ub3d9\u00a0CEO\uc778\u00a0Alex Zhavoronkov \ubc15\uc0ac\ub294\u00a0“\ub2f9\uc0ac\uc758\u00a0\ucd5c\uc2e0\u00a0\uc0dd\uc131\ud615\u00a0AI\ub85c\u00a0\uace0\uc548\ub41c\u00a0\uc694\ubc95\uc774\u00a0\uc720\ubc29\uc554\u00a0\ud658\uc790\uc5d0\uac8c\u00a0\uc0c8\ub85c\uc6b4\u00a0\uc7a0\uc7ac\uc801\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\uc81c\uacf5\ud560\u00a0\uac00\ub2a5\uc131\uc774\u00a0\uc788\ub2e4\ub294\u00a0\ub370\u00a0\uc815\ub9d0\u00a0\uae30\uc058\ub2e4”\uba70\u00a0” Stemline\uc740\u00a0\ud601\uc2e0\uc801\uc778\u00a0\ube44\uc804\uc744\u00a0\uac00\uc9c0\uace0\u00a0\uc788\uace0\u00a0\uc885\uc591\ud559\uc5d0\uc11c\u00a0\uc804\ud658\uc801\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\uc81c\uacf5\ud558\ub294\u00a0\ub370\u00a0\ud070\u00a0\uc911\uc810\uc744\u00a0\ub450\uace0\u00a0\uc788\uc5b4\u00a0\uc774\u00a0\ubd84\uc790\ub97c\u00a0\uac1c\ubc1c\ud558\uace0\u00a0\uc784\uc0c1\uc2dc\ud5d8\uc744\u00a0\uc9c4\ud589\ud558\ub294\u00a0\ub370\u00a0\uc788\uc5b4\u00a0\uc774\uc0c1\uc801\uc778\u00a0\ud30c\ud2b8\ub108”\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n \uc774\u00a0\uacc4\uc57d\u00a0\uc870\uac74\uc5d0\uc11c\u00a0Stemline\uc740\u00a0InSilico\uc5d0\u00a01200\ub9cc\u00a0\ubd88\uc744\u00a0\uc120\uc9c0\uae09\ud560\u00a0\uac83\uc774\ub2e4. \ubaa8\ub4e0\u00a0\uac1c\ubc1c, \uaddc\uc81c, \uc0c1\uc6a9\u00a0\ub9c8\uc77c\uc2a4\ud1a4\uc744\u00a0\ud3ec\ud568\ud558\uc5ec\u00a0\uc774\u00a0\uac70\ub798\uc758\u00a0\ubcf5\ud569\u00a0\uac00\uce58\ub294\u00a05\uc5b5\u00a0\ubd88\u00a0\uc774\uc0c1\uc774\uba70\u00a0\ub85c\uc5f4\ud2f0\ub294\u00a0\ub450\u00a0\uc790\ub9bf\uc218\uc5d0\u00a0\ub2ec\ud55c\ub2e4.<\/p>\n Menarini Group\uc5d0\u00a0\ub300\ud574\u00a0<\/p>\n Menarini Group\uc740 \ub9e4\ucd9c\uc774 44\uc5b5 \ub2ec\ub7ec \uc774\uc0c1\uc774\uace0 17,000\uba85\uc774 \ub118\ub294 \uc9c1\uc6d0\uc744 \ub454 \uc120\ub3c4\uc801\uc778 \uad6d\uc81c \uc81c\uc57d \ubc0f \uc9c4\ub2e8 \ud68c\uc0ac\uc774\ub2e4. Menarini\ub294 \uc2ec\uc7a5\ud559, \uc885\uc591\ud559, \ud638\ud761\uae30\ud559, \uc18c\ud654\uae30\ud559, \uac10\uc5fc \uc9c8\ud658, \ub2f9\ub1e8\ubcd1, \uc5fc\uc99d \ubc0f \uc9c4\ud1b5 \uc758\uc57d\ud488\uc73c\ub85c \ubd80\ud569\ub418\uc9c0 \uc54a\ub294 \uc218\uc694\uac00 \ub192\uc740 \uce58\ub8cc \uc601\uc5ed\uc5d0 \uc911\uc810\uc744 \ub454\ub2e4. 18\uac1c \uc81c\uc870\uc18c\uc640 9\uac1c \uc5f0\uad6c\uac1c\ubc1c \uc13c\ud130\uac00 \uc788\ub294 Menarini Group\uc758 \uc758\uc57d\ud488\uc740 \uc804 \uc138\uacc4 140\uac1c\uad6d\uc5d0 \uc81c\uacf5\ub41c\ub2e4. \ucd94\uac00 \uc815\ubcf4\ub294 menarini.com\uc744 \ucc38\uc870\ud55c\ub2e4.<\/p>\n Stemline Therapeutics, Inc.,\uc5d0\u00a0\ub300\ud574<\/p>\n Stemline Therapeutics, Inc.,\uc740 Menarini Group\uc758 \uc644\uc804 \uc18c\uc720 \uc790\ud68c\uc0ac\ub85c \uc0c8\ub85c\uc6b4 \uc554 \uce58\ub8cc\uc81c\uc758 \uac1c\ubc1c \ubc0f \uc0c1\uc6a9\ud654\uc5d0 \uc911\uc810\uc744 \ub454 \uc0c1\uc6a9 \ub2e8\uacc4 \uc0dd\ubb3c\uc758\uc57d\ud488 \ud68c\uc0ac\uc774\ub2e4. Stemline\uc740 \ubbf8\uad6d\uacfc \uc720\ub7fd \uc5f0\ud569\uc5d0\uc11c \ud558\ub098 \uc774\uc0c1\uc758 \ub0b4\ubd84\ube44 \uc694\ubc95 \ud6c4 \uc9c8\ubcd1 \uc9c4\ud589\uc744 \ubcf4\uc778 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uc6a9\uccb4(ER) \uc591\uc131, \uc778\uac04 \uc0c1\ud53c\uc131\uc7a5\uc778\uc790 \uc218\uc6a9\uccb4 1(HER2) \uc74c\uc131, ESR1 \ub3cc\uc5f0\ubcc0\uc774 \uc9c4\ud589\uc131 \ub610\ub294 \uc804\uc774\uc131 \uc720\ubc29\uc554\uc774 \uc788\ub294 \ud3d0\uacbd \ud6c4 \uc5ec\uc131 \ub610\ub294 \uc131\uc778 \ub0a8\uc131\uc758 \uce58\ub8cc\uc5d0 \uc801\uc751\ub418\ub294 \uacbd\uad6c \ub0b4\ubd84\ube44 \uc694\ubc95\uc778 ORSERDU\u00ae(elacestrant)\ub97c \uc2dc\ud310\ud558\uace0 \uc788\ub2e4. Stemline\uc740 \uacf5\uaca9\uc801 \ud608\uc561\uc554\uc778 \ubaa8\uad6c \ud615\uc9c8\uc138\ud3ec\uc591 \uc218\uc9c0\uc138\ud3ec \uc885\uc591(BPDCN) \ud658\uc790\uc5d0\uc11c CD123\uc744 \ud45c\uc801\ud558\ub294 \uc0c8\ub85c\uc6b4 \ud45c\uc801 \uce58\ub8cc\uc81c\uc778 ELZONRIS\u00ae(\uc131\ubd84\uba85: tagraxofusp-erzs)\ub3c4 \ubbf8\uad6d\uacfc \uc720\ub7fd\uc5d0\uc11c \ud310\ub9e4\ud558\uace0 \uc788\ub2e4. \uc774\ub294 \ud604\uc7ac\uae4c\uc9c0 \ubbf8\uad6d\uacfc \uc720\ub7fd\uc5f0\ud569\uc5d0\uc11cBPDCN\uc5d0 \ub300\ud574 \uc2b9\uc778\ub41c \uc720\uc77c\ud55c \uce58\ub8cc\uc81c\uc774\ub2e4. Stemline\uc740 \ub2e4\ubc1c\uc131 \uace8\uc218\uc885\uc5d0 \ub300\ud55c XPO1 \uc5b5\uc81c\uc81c\uc778 NEXPOVIO\u00ae(\uc131\ubd84\uba85: Selinexor)\ub3c4 \uc720\ub7fd\uc5d0\uc11c \ud310\ub9e4\ud558\uace0 \uc788\ub2e4. Stemline\uc740 \uc5ec\ub7ec \uace0\ud615\uc554 \ubc0f \ud608\uc561\uc554\uc5d0 \ub300\ud574 \uc5ec\ub7ec \ub2e8\uacc4\ub85c \uac1c\ubc1c\ub418\uace0 \uc788\ub294 \uad11\ubc94\uc704\ud55c \uc18c\ubd84\uc790 \ubc0f \uc0dd\ubb3c\ud559\uc801 \uc758\uc57d\ud488 \uc784\uc0c1 \ud30c\uc774\ud504\ub77c\uc778\ub3c4 \ubcf4\uc720\ud558\uace0 \uc788\ub2e4.<\/p>\n InSilico Medicine\uc5d0\u00a0\ub300\ud574<\/p>\n InSilico Medicine\uc740\u00a0\uc0dd\uc131\ud615\u00a0AI\ub97c\u00a0\uac16\ucd98\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\ud68c\uc0ac\ub85c\u00a0\ucc28\uc138\ub300\u00a0AI \uc2dc\uc2a4\ud15c\uc744\u00a0\uc0ac\uc6a9\ud574\u00a0\uc0dd\ubb3c\ud559, \ud654\ud559, \uc784\uc0c1\uc2dc\ud5d8\uc744\u00a0\uc5f0\uacb0\ud55c\ub2e4. \uc774\u00a0\ud68c\uc0ac\ub294\u00a0\uc0c8\ub85c\uc6b4\u00a0\ud45c\uc801\uc744\u00a0\ubc1c\uacac\ud558\uace0\u00a0\uc6d0\ud558\ub294\u00a0\uc18d\uc131\uc758\u00a0\uc0c8\ub85c\uc6b4\u00a0\ubd84\uc790\u00a0\uad6c\uc870\ub97c\u00a0\uc0dd\uc131\ud558\uae30\u00a0\uc704\ud574\u00a0\ub525\u00a0\uc0dd\uc131\u00a0\ubaa8\ub378, \uac15\ud654\u00a0\ud559\uc2b5, \ubcc0\ud658\uae30\u00a0\ubc0f\u00a0\uae30\ud0c0\u00a0\ud604\ub300\uc2dd\u00a0\uba38\uc2e0\u00a0\ub7ec\ub2dd\u00a0\uae30\uc220\uc744\u00a0\uc774\uc6a9\ud558\ub294\u00a0AI \ud50c\ub7ab\ud3fc\uc744\u00a0\uac1c\ubc1c\ud588\ub2e4. InSilico Medicine\uc740\u00a0\uc554, \uc12c\uc720\uc99d, \uba74\uc5ed, \uc911\ucd94\uc2e0\uacbd\uacc4\u00a0\uc9c8\ud658, \uac10\uc5fc\u00a0\uc9c8\ud658, \uc790\uac00\uba74\uc5ed\u00a0\uc9c8\ud658\u00a0\ubc0f\u00a0\ub178\ud654\u00a0\uad00\ub828\u00a0\uc9c8\ud658\uc5d0\u00a0\ub300\ud55c\u00a0\ud601\uc2e0\uc801\uc778\u00a0\uc57d\ubb3c\uc744\u00a0\ubc1c\uacac\ud558\uace0\u00a0\uac1c\ubc1c\ud558\ub294\u00a0\ud68d\uae30\uc801\uc778\u00a0\uc194\ub8e8\uc158\uc744\u00a0\uac1c\ubc1c\ud558\uace0\u00a0\uc788\ub2e4. www.insilico.com<\/a><\/p>\n 1 Sung\u00a0H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021 Feb 4<\/span>. doi: 10.3322\/caac.21660. Epub ahead of print. 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