{"id":20066,"date":"2023-12-05T02:19:31","date_gmt":"2023-12-04T17:19:31","guid":{"rendered":"http:\/\/mhjn.dothome.co.kr\/insilico-medicine-%ea%b2%bd%ea%b5%ac%ec%9a%a9-phd-%ec%96%b5%ec%a0%9c%ec%a0%9c-%ec%9e%84%ec%83%81-%ec%b0%a9%ec%88%98\/"},"modified":"2023-12-05T02:19:31","modified_gmt":"2023-12-04T17:19:31","slug":"insilico-medicine-%ea%b2%bd%ea%b5%ac%ec%9a%a9-phd-%ec%96%b5%ec%a0%9c%ec%a0%9c-%ec%9e%84%ec%83%81-%ec%b0%a9%ec%88%98","status":"publish","type":"post","link":"https:\/\/mhjn.dothome.co.kr\/en\/insilico-medicine-%ea%b2%bd%ea%b5%ac%ec%9a%a9-phd-%ec%96%b5%ec%a0%9c%ec%a0%9c-%ec%9e%84%ec%83%81-%ec%b0%a9%ec%88%98\/","title":{"rendered":"Insilico Medicine, \uacbd\uad6c\uc6a9 PHD \uc5b5\uc81c\uc81c \uc784\uc0c1 \ucc29\uc218"},"content":{"rendered":"

ISM5411\ub294 \uacbd\uad6c\ud615 PHD \ud2b9\uc774\uc5b5\uc81c\uc81c\ub85c \uc7a5\ub0b4 \ubc29\uc5b4\ubcbd \ubcf4\ud638 \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc720\ub3c4\ud558\uc5ec IBD \uce58\ub8cc \ucd09\uc9c4 ISM5411\ub294 Insilico Medicine\uc774 \uc784\uc0c1 \uc2e4\ud5d8\uc5d0 \ub3cc\uc785\ud55c \ub2e4\uc12f \ubc88\uc9f8 \uc778\uacf5\uc9c0\ub2a5 \uae30\ubc18 \uc57d\ubb3c \ud504\ub85c\uadf8\ub7a8\uc73c\ub85c, \uac74\uac15\ud55c \ud53c\ud5d8\uc790 \ub300\uc0c1\uc758 \uccab \ud22c\uc57d\uc744 \ud638\uc8fc\uc5d0\uc11c \uc644\ub8cc ISM5411\uc758 \ud6a8\uacfc\ub97c \ub354 \ub9ce\uc740 \uc778\uad6c\uc5d0 \ud14c\uc2a4\ud2b8\ud558\uae30 \uc704\ud574, Insilico\ub294 \uc784\uc0c1 1a \uc0c1\uc5d0 \uc774\uc5b4, \uc804 \uc138\uacc4 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \ub2e4\uae30\uad00 1b\uc0c1 \uc2e4\ud5d8\uc744 \uc9c4\ud589\ud560 \uacc4\ud68d <\/p>\n

\ub274\uc695, \ud64d\ucf69\u00a02023\ub144\u00a012\uc6d4\u00a05\uc77c\u00a0\/PRNewswire=\uc5f0\ud569\ub274\uc2a4\/ — \uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5(AI) \uae30\ubc18\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\uae30\uc5c5\uc778\u00a0Insilico Medicine(\uc774\ud558\u00a0‘Insilico’)\uac00\u00a0\uc624\ub298\u00a0\uc5fc\uc99d\uc131\u00a0\uc7a5\uc9c8\ud658(IBD) \uce58\ub8cc\ub97c\u00a0\uc704\ud55c\u00a0\uc138\uacc4\u00a0\ucd5c\ucd08\u00a0PHD \uc5b5\uc81c\uc81c\u00a0\ud6c4\ubcf4\u00a0\ubb3c\uc9c8\uc778\u00a0ISM5411\uc758\u00a0\uc784\uc0c1\uc2e4\ud5d8\uc744\u00a0\uc2dc\uc791\ud588\ub2e4\uace0\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n

Insilico\uc758 \ub3c5\uc810\uc801\uc778 \uc5d4\ub4dc \ud22c \uc5d4\ub4dc(end-to-end) \uc778\uacf5\uc9c0\ub2a5 \uc2e0\uc57d \uac1c\ubc1c \ud50c\ub7ab\ud3fc\uc778 Pharma.AI\ub85c \uac1c\ubc1c\ub41c ISM5411\uc740 Insilico\uac00 5 \ubc88\uc9f8\ub85c \uc784\uc0c1 \uc2e4\ud5d8\uc744 \uc9c4\ud589\ud558\ub294 \uc57d\ud488\uc774\ub2e4. \ud604\uc7ac \uc9c4\ud589 \uc911\uc778 \uc784\uc0c1 1\uc0c1[https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT06012578?term=ISM5411-101&draw=2&rank=1<\/a>\u00a0] \uc740 76\uba85\uc758 \uac74\uac15\ud55c \ud53c\ud5d8\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \uacbd\uad6c \uc6a9\ub7c9 \uc99d\uac00\uc5d0 \ub530\ub978 ISM5411\uc758 \uc548\uc815\uc131, \ub0b4\uc57d\uc131, \uc57d\ub3d9\ud559 \ubc0f \uc2dd\uc774 \ud6a8\uacfc\ub97c \ud3c9\uac00\ud558\ub3c4\ub85d \uc124\uacc4\ub418\uc5c8\uc73c\uba70 \uac74\uac15\ud55c \ud53c\ud5d8\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uccab \ud22c\uc57d\uc740 \ud638\uc8fc\uc5d0\uc11c \uc644\ub8cc\ub418\uc5c8\ub2e4. \ub354 \ub9ce\uc740 \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c ISM5411\uc758 \ud6a8\uacfc\ub97c \ud3c9\uac00\ud558\uae30 \uc704\ud574 Insilico\ub294 \uc784\uc0c1 1a \uc0c1\uc5d0 \uc774\uc5b4, \uc804 \uc138\uacc4 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \ub2e4\uae30\uad00 1b\uc0c1 \uc2e4\ud5d8\uc744 \uc9c4\ud589\ud560 \uacc4\ud68d\uc774\ub2e4.<\/p>\n

\uc774\ubc88\u00a0\uc784\uc0c1\uc2e4\ud5d8\uc744\u00a0\uc8fc\ub3c4\ud558\uace0\u00a0\uc788\ub294\u00a0Insilico\uc758\u00a0\ucd5c\uace0\uc758\ub8cc\ucc45\uc784\uc790\uc778\u00a0Sujata Rao \uc758\ud559\ubc15\uc0ac\ub294\u00a0‘IBD\ub294\u00a0\uce58\ub8cc\u00a0\uc120\ud0dd\uc9c0\uac00\u00a0\uc81c\ud55c\ub41c\u00a0\ub9ce\uc740\u00a0\ud658\uc790\ub4e4\uc5d0\u00a0\uc601\ud5a5\uc744\u00a0\ub07c\uce58\uace0\u00a0\uc788\ub2e4’\uba70\u00a0‘\uc138\uacc4\u00a0\ucd5c\ucd08\uc758\u00a0\uac00\ub2a5\uc131\uc774\u00a0\uc788\ub294\u00a0\uc774\u00a0\uce58\ub8cc\ubc95\uc774\u00a0\uc720\ub9dd\ud55c\u00a0\ub300\uccb4\uc81c\ub85c\uc368\uc758\u00a0\uc5ed\ud560\uc744\u00a0\ud560\u00a0\uc218\u00a0\uc788\uc744\u00a0\uac83\uc774\ub77c\uace0\u00a0\uc0dd\uac01\ud55c\ub2e4’\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n

IBD[https:\/\/pubmed.ncbi.nlm.nih.gov\/24833941\/<\/a>\u00a0]\ub294 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc(UC)\uacfc \ud06c\ub860\ubcd1(CD)\uc744 \ud3ec\ud568\ud55c \uc704\uc7a5\uad00 \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658\uc73c\ub85c \uc804 \uc138\uacc4\uc801\uc73c\ub85c \ub9ce\uc740 \uc778\uad6c\uac00 \uc553\uace0 \uc788\ub294\ub370 \ubbf8\uad6d\uc5d0\uc11c\ub9cc \uc131\uc778 2\ubc31\ub9cc \uba85\uc774 \uc99d\uc0c1\uc744 \uc553\uace0 \uc788\ub2e4. \uc774 \uc9c8\ud658\uc740 \uce58\ub8cc \ubd88\uac00\ud560 \ubfd0 \uc544\ub2c8\ub77c \ub300\uc7a5\uc554 \ubc1c\ubcd1\ub960\uc744 4\ubc30 \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \ud604\uc7ac IBD \uce58\ub8cc\ubc95\uc778 \ud56d\uc5fc\uc99d\uc81c\ub294 \uae0d\uc815\uc801\uc778 \uc608\ud734\uc640 \ubc00\uc811\ud55c \uc5f0\uad00\uc774 \uc788\ub294 \uc810\ub9c9 \uce58\uc720\ub97c \uc81c\ud55c\uc801\uc73c\ub85c \uac1c\uc120\ud558\ub294 \ud6a8\uacfc\ub9cc \uc788\uace0 \uc54c\ub824\uc838 \uc788\ub2e4.<\/p>\n

\uc5f0\uad6c\u00a0\uacb0\uacfc\uc5d0\u00a0\ub530\ub974\uba74\u00a0PHD\ub294\u00a0\uc7a5\ub0b4\u00a0\ubc29\uc5b4\ubcbd\u00a0\ubcf4\ud638\u00a0\uc720\uc804\uc790\uc758\u00a0\ubc1c\ud604\uc744\u00a0\uc720\ub3c4\ud558\ub294\u00a0\uc800\uc0b0\uc18c\uc99d\u00a0\uc720\ub3c4\uc778\uc790(HIF-1\u03b1)\uc758\u00a0\uc548\uc815\uc131\uacfc\u00a0\uc804\uc0ac\u00a0\ud65c\ub3d9\u00a0\uc870\uc808\uc5d0\u00a0\uc911\uc694\ud55c\u00a0\uc5ed\ud560\uc744\u00a0\ud55c\ub2e4. PHD\ub294\u00a0IBD \ud658\uc790\uc5d0\uc11c\u00a0\uc720\ud6a8\ud558\uac8c\u00a0\uc0c1\ud5a5\u00a0\uc870\uc808\ub418\uc5c8\uace0\u00a0\uc5fc\uc99d\uc131\u00a0\uc0ac\uc774\ud1a0\uce74\uc778\u00a0\ubc0f\u00a0\uc138\ud3ec\u00a0\uc0ac\uba78\u00a0\ub9c8\ucee4\uc758\u00a0\ubc1c\ud604\uacfc\u00a0\ub192\uc740\u00a0\uc0c1\uad00\uad00\uacc4\ub97c\u00a0\ubcf4\uc600\ub294\ub370, \uc774\ub294\u00a0IBD \uce58\ub8cc\uc5d0\u00a0PHD\ub97c\u00a0\uc7a0\uc7ac\ub825\uc744\u00a0\uac00\uc9c0\uace0\u00a0\uc788\ub2e4\ub294\u00a0\uac83\uc744\u00a0\uc758\ubbf8\ud55c\ub2e4.<\/p>\n

2022\ub144\u00a01\uc6d4\u00a0Insilico\ub294PHD\ub97c\u00a0\ud0c0\uac9f\ud55c\u00a0IBD \uce58\ub8cc\uc5d0\u00a0ISM5411\uc744\u00a0\uc804\uc784\uc0c1\u00a0\uc2e4\ud5d8\u00a0\ud6c4\ubcf4(PCC)\ub85c\u00a0\uc120\uc815\ud588\ub2e4. ISM5411\ub294\u00a0Insilico\uc758\u00a0\ubd84\uc790\u00a0\uac1c\ubc1c\uc744\u00a0\uc704\ud55c\u00a0\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc5d4\uc9c4\uc778\u00a0Chemistry42\ub97c\u00a0\uc0ac\uc6a9\ud558\uc5ec\u00a0\uac1c\ubc1c\ub410\uc73c\uba70\u00a0\uc0c8\ub85c\uc6b4\u00a0\uc2a4\uce90\ud3f4\ub4dc\uc640\u00a0\ud2b9\uc218\ud55c\u00a0\ubc14\uc778\ub529\u00a0\ubaa8\ub4dc\uac00\u00a0\ud2b9\uc9d5\uc774\ub2e4. \uc804\uc784\uc0c1\u00a0\ub2e8\uacc4\uc5d0\uc11c\u00a0ISM5411\ub294\u00a0\uacbd\uad6c\uc6a9\u00a0\uc7a5\ub0b4\u00a0\uc81c\ud55c\uc801\u00a0\uc800\ubd84\uc790\u00a0\uc5b5\uc81c\uc81c\ub85c\uc11c\u00a0\uc591\ud638\ud55c\u00a0\uc548\uc804\uc131\u00a0\uc815\ubcf4\uc640\u00a0\ud6a8\uacfc\uc801\uc778\u00a0\ud56d\ub300\uc7a5\uc5fc\u00a0\ud6a8\ub2a5\uc744\u00a0\uc785\uc99d\ud55c\u00a0\ubc14\u00a0\uc788\ub2e4.\u00a0<\/p>\n

Insilico\uc758\u00a0\uacf5\ub3d9\u00a0\ucd5c\uace0\uacbd\uc601\ucc45\uc784\uc790\uc774\uc790\u00a0\ucd5c\uace0\uacfc\ud559\ucc45\uc784\uc790\uc778\u00a0Feng Ren \ubc15\uc0ac\ub294\u00a0‘IBD\uc758\u00a0\ubc1c\ubcd1\ub960\uc758\u00a0\uc99d\uac00\ub294\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc758\ub8cc\u00a0\uc2dc\uc2a4\ud15c\uc5d0\u00a0\ud070\u00a0\ubd80\ub2f4\uc73c\ub85c\u00a0\uc791\uc6a9\ud55c\ub2e4’\uba70\u00a0‘\uc778\uacf5\uc9c0\ub2a5\uc774\u00a0\ub514\uc790\uc778\ud55c\u00a0ISM5411\uc740\u00a0\uc7a5\ub0b4\u00a0\ubc29\uc5b4\ubcbd\u00a0\ubcf4\ud638\u00a0\uac15\ud654\ub77c\ub294\u00a0\ub3c5\ud2b9\ud55c\u00a0\uba54\ucee4\ub2c8\uc998\uc73c\ub85c\u00a0\uc810\ub9c9\uc744\u00a0\uce58\uc720\ud558\ub3c4\ub85d\u00a0\uc124\uacc4\ub418\uc5c8\ub294\ub370\u00a0\uc774\ub294\u00a0IBD \ud658\uc790\uc758\u00a0\ud601\uc2e0\uc801\uc778\u00a0\uce58\ub8cc\u00a0\ubc29\uc2dd\uc73c\ub85c\u00a0\ucc44\ud0dd\ub420\u00a0\uc218\u00a0\uc788\ub294\u00a0\uc7a0\uc7ac\ub825\uc744\u00a0\uc9c0\ub2cc\ub2e4. ISM5411 \uc784\uc0c1\uc2e4\ud5d8\uc744\u00a0\ucd09\uc9c4\ud558\uc5ec\u00a0\uc784\uc0c1\uc758\u00a0\uc694\uad6c\uc0ac\ud56d\uc744\u00a0\ucda9\uc871\ud560\u00a0\uc218\u00a0\uc788\ub3c4\ub85d\u00a0\ucd5c\uc120\uc744\u00a0\ub2e4\ud558\uaca0\ub2e4’\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n

\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uae30\ubc18\uc758\u00a0Insilico\ub294\u00a0\uc778\uacf5\uc9c0\ub2a5\uacfc\u00a0\ucd5c\ucca8\ub2e8\u00a0\uae30\uc220\uc758\u00a0\uad50\ucc28\uc810\uc5d0\u00a0\uc11c\u00a0\uc788\ub2e4. \ub610\ud55c\u00a0\uc0dd\ubb3c\ud559, \ud654\ud559, \uadf8\ub9ac\uace0\u00a0\uc784\uc0c1\u00a0\uac1c\ubc1c\uc744\u00a0\ud55c\u00a0\ub370\u00a0\uc787\ub294\u00a0\ud1b5\ud569\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uae30\ubc18\u00a0\uc2e0\uc57d\u00a0\uac1c\ubc1c\u00a0\ud50c\ub7ab\ud3fc\uc778\u00a0Pharma.AI\ub97c\u00a0\ud65c\uc6a9\ud558\uc5ec\u00a030\uc5ec\uac1c\uc758\u00a0\ud30c\uc774\ud504\ub77c\uc778\uc744\u00a0\ubcf4\uc720\ud558\uace0\u00a0\uc788\uc73c\uba70\u00a0\uc774\u00a0\uc911\u00a05\uac1c\ub294\u00a0\uc784\uc0c1\u00a0\uc2e4\ud5d8\u00a0\ub2e8\uacc4\uc5d0\u00a0\uc788\ub2e4. \ucd5c\uadfc\u00a0Insilico\ub294\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc54c\uace0\ub9ac\uc998\u00a0\uc5f0\uad6c\uc640\u00a0\ud50c\ub7ab\ud3fc\u00a0\uac1c\ubc1c\u00a0\uc5ed\ub7c9\u00a0\uac15\ud654\ub97c\u00a0\uc704\ud574\u00a0\uce90\ub098\ub2e4\u00a0\ubaac\ud2b8\ub9ac\uc62c\uc5d0\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc5f0\uad6c\uac1c\ubc1c\u00a0\uc13c\ud130\ub97c\u00a0\ubc1c\uc871\ud588\ub2e4.<\/p>\n

Insilico\uc758\u00a0\ucc3d\ub9bd\uc790\uc774\uc790\u00a0\uacf5\ub3d9\u00a0\ucd5c\uace0\uacbd\uc601\ucc45\uc784\uc790\uc778\u00a0Alex Zhavoronkoy\ub294\u00a0‘\ub2f9\uc0ac\ub294\u00a0\uc778\uac04\uc758\u00a0\ub3c5\ucc3d\uc131\uacfc\u00a0\uacb0\ud569\ub41c\u00a0\ucd5c\ucca8\ub2e8\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uae30\uc220\uc744\u00a0\uc0ac\uc6a9\ud558\uc5ec\u00a0\ud658\uc790\ub97c\u00a0\ub3d5\uae30\u00a0\uc704\ud574\u00a0\ub178\ub825\ud558\uace0\u00a0\uc788\ub2e4’\uba70\u00a0‘\uc774\ubc88\u00a0IBD \ud504\ub85c\uadf8\ub7a8\uc740\u00a0\uc5b4\ub824\uc6b4\u00a0\uc9c8\ubcd1\uc5d0\u00a0\uc0c8\ub85c\uc6b4\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\ub3c4\uc785\ud558\uae30\u00a0\uc704\ud574\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc54c\uace0\ub9ac\uc998\uc744\u00a0\uc0ac\uc6a9\ud558\ub294\u00a0\ucd5c\uc2e0\u00a0\uc0ac\ub840\uc774\ub2e4’\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n

Insilico Medicine \uc18c\uac1c<\/p>\n

\uae00\ub85c\ubc8c\u00a0\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5(AI) \uae30\ubc18\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\uae30\uc5c5\uc778\u00a0Insilico Medicine\uc740\u00a0\ucc28\uc138\ub300\u00a0\uc778\uacf5\uc9c0\ub2a5\uc744\u00a0\ud65c\uc6a9\ud558\uc5ec\u00a0\uc0dd\ubb3c\ud559, \ud654\ud559, \uadf8\ub9ac\uace0\u00a0\uc784\uc0c1\u00a0\uc2e4\ud5d8\u00a0\ubd84\uc11d\uc744\u00a0\uacb0\ud569\ud55c\ub2e4. \uc774\u00a0\ud68c\uc0ac\ub294\u00a0\uc2e0\uaddc\u00a0\ud0c0\uae43\u00a0\ubc1c\uacac\uacfc\u00a0\uc6d0\ud558\ub294\u00a0\ud2b9\uc131\uc744\u00a0\uac00\uc9c4\u00a0\uc2e0\uaddc\u00a0\ubd84\uc790\u00a0\uad6c\uc870\u00a0\uc0dd\uc131\uc744\u00a0\uc704\ud574\u00a0\uc2ec\uce35\u00a0\uc0dd\uc131\u00a0\ubaa8\ub378, \uac15\ud654\u00a0\ud559\uc2b5, \ud2b8\ub79c\uc2a4\ud3ec\uba38\u00a0\ub4f1\uacfc\u00a0\uac19\uc740\u00a0\ud604\ub300\u00a0\uae30\uacc4\u00a0\ud559\uc2b5\u00a0\uae30\uc220\uc744\u00a0\uc0ac\uc6a9\ud558\ub294\u00a0\uc778\uacf5\u00a0\uc9c0\ub2a5\u00a0\ud50c\ub7ab\ud3fc\uc744\u00a0\uac1c\ubc1c\ud588\ub2e4. Insilico Medicine\uc740\u00a0\uc554, \uc12c\uc720\ud654, \uba74\uc5ed, \uc911\ucd94\uc2e0\uacbd\uacc4\u00a0\uc9c8\ud658, \uac10\uc5fc\uc131\u00a0\uc9c8\ud658, \uc790\uac00\uba74\uc5ed\u00a0\uc9c8\ud658, \ub178\ud654\u00a0\uad00\ub828\u00a0\uc9c8\ud658\u00a0\ub4f1\uc744\u00a0\uce58\ub8cc\ud558\uae30\u00a0\uc704\ud55c\u00a0\uc2e0\uc57d\uc744\u00a0\uac1c\ubc1c\ud558\ub294\u00a0\ud601\uc2e0\uc801\uc778\u00a0\uc194\ub8e8\uc158\uc744\u00a0\uac1c\ubc1c\ud558\ub294\u00a0\ub370\u00a0\uc9d1\uc911\ud55c\ub2e4.<\/p>\n

www.insilico.com<\/a><\/p>","protected":false},"excerpt":{"rendered":"

<\/p>\n

ISM5411\ub294 \uacbd\uad6c\ud615 PHD \ud2b9\uc774\uc5b5\uc81c\uc81c\ub85c \uc7a5\ub0b4 \ubc29\uc5b4\ubcbd \ubcf4\ud638 \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc720\ub3c4\ud558\uc5ec IBD \uce58\ub8cc \ucd09\uc9c4 ISM5411\ub294 Insilico Medicine\uc774 \uc784\uc0c1 \uc2e4\ud5d8\uc5d0 \ub3cc\uc785\ud55c \ub2e4\uc12f \ubc88\uc9f8 \uc778\uacf5\uc9c0\ub2a5 \uae30\ubc18 \uc57d\ubb3c \ud504\ub85c\uadf8\ub7a8\uc73c\ub85c, \uac74\uac15\ud55c \ud53c\ud5d8\uc790 \ub300\uc0c1\uc758 \uccab \ud22c\uc57d\uc744 \ud638\uc8fc\uc5d0\uc11c \uc644\ub8cc ISM5411\uc758 \ud6a8\uacfc\ub97c \ub354 \ub9ce\uc740 \uc778\uad6c\uc5d0 \ud14c\uc2a4\ud2b8\ud558\uae30 \uc704\ud574, Insilico\ub294 \uc784\uc0c1 1a \uc0c1\uc5d0 \uc774\uc5b4, \uc804 \uc138\uacc4 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \ub2e4\uae30\uad00 1b\uc0c1 \uc2e4\ud5d8\uc744 \uc9c4\ud589\ud560 \uacc4\ud68d <\/p>\n

\ub274\uc695, \ud64d\ucf69\u00a02023\ub144\u00a012\uc6d4\u00a05\uc77c\u00a0\/PRNewswire=\uc5f0\ud569\ub274\uc2a4\/ — \uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5(AI) \uae30\ubc18\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\uae30\uc5c5\uc778\u00a0Insilico Medicine(\uc774\ud558\u00a0‘Insilico’)\uac00\u00a0\uc624\ub298\u00a0\uc5fc\uc99d\uc131\u00a0\uc7a5\uc9c8\ud658(IBD) \uce58\ub8cc\ub97c\u00a0\uc704\ud55c\u00a0\uc138\uacc4\u00a0\ucd5c\ucd08\u00a0PHD \uc5b5\uc81c\uc81c\u00a0\ud6c4\ubcf4\u00a0\ubb3c\uc9c8\uc778\u00a0ISM5411\uc758\u00a0\uc784\uc0c1\uc2e4\ud5d8\uc744\u00a0\uc2dc\uc791\ud588\ub2e4\uace0\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n

Insilico\uc758 \ub3c5\uc810\uc801\uc778 \uc5d4\ub4dc \ud22c \uc5d4\ub4dc(end-to-end) \uc778\uacf5\uc9c0\ub2a5 \uc2e0\uc57d \uac1c\ubc1c \ud50c\ub7ab\ud3fc\uc778 Pharma.AI\ub85c \uac1c\ubc1c\ub41c ISM5411\uc740 Insilico\uac00 5 \ubc88\uc9f8\ub85c \uc784\uc0c1 \uc2e4\ud5d8\uc744 \uc9c4\ud589\ud558\ub294 \uc57d\ud488\uc774\ub2e4. \ud604\uc7ac \uc9c4\ud589 \uc911\uc778 \uc784\uc0c1 1\uc0c1[https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT06012578?term=ISM5411-101&draw=2&rank=1<\/a>\u00a0] \uc740 76\uba85\uc758 \uac74\uac15\ud55c \ud53c\ud5d8\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \uacbd\uad6c \uc6a9\ub7c9 \uc99d\uac00\uc5d0 \ub530\ub978 ISM5411\uc758 \uc548\uc815\uc131, \ub0b4\uc57d\uc131, \uc57d\ub3d9\ud559 \ubc0f \uc2dd\uc774 \ud6a8\uacfc\ub97c \ud3c9\uac00\ud558\ub3c4\ub85d \uc124\uacc4\ub418\uc5c8\uc73c\uba70 \uac74\uac15\ud55c \ud53c\ud5d8\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uccab \ud22c\uc57d\uc740 \ud638\uc8fc\uc5d0\uc11c \uc644\ub8cc\ub418\uc5c8\ub2e4. \ub354 \ub9ce\uc740 \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c ISM5411\uc758 \ud6a8\uacfc\ub97c \ud3c9\uac00\ud558\uae30 \uc704\ud574 Insilico\ub294 \uc784\uc0c1 1a \uc0c1\uc5d0 \uc774\uc5b4, \uc804 \uc138\uacc4 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \ub2e4\uae30\uad00 1b\uc0c1 \uc2e4\ud5d8\uc744 \uc9c4\ud589\ud560 \uacc4\ud68d\uc774\ub2e4.<\/p>\n

\uc774\ubc88\u00a0\uc784\uc0c1\uc2e4\ud5d8\uc744\u00a0\uc8fc\ub3c4\ud558\uace0\u00a0\uc788\ub294\u00a0Insilico\uc758\u00a0\ucd5c\uace0\uc758\ub8cc\ucc45\uc784\uc790\uc778\u00a0Sujata Rao \uc758\ud559\ubc15\uc0ac\ub294\u00a0‘IBD\ub294\u00a0\uce58\ub8cc\u00a0\uc120\ud0dd\uc9c0\uac00\u00a0\uc81c\ud55c\ub41c\u00a0\ub9ce\uc740\u00a0\ud658\uc790\ub4e4\uc5d0\u00a0\uc601\ud5a5\uc744\u00a0\ub07c\uce58\uace0\u00a0\uc788\ub2e4’\uba70\u00a0‘\uc138\uacc4\u00a0\ucd5c\ucd08\uc758\u00a0\uac00\ub2a5\uc131\uc774\u00a0\uc788\ub294\u00a0\uc774\u00a0\uce58\ub8cc\ubc95\uc774\u00a0\uc720\ub9dd\ud55c\u00a0\ub300\uccb4\uc81c\ub85c\uc368\uc758\u00a0\uc5ed\ud560\uc744\u00a0\ud560\u00a0\uc218\u00a0\uc788\uc744\u00a0\uac83\uc774\ub77c\uace0\u00a0\uc0dd\uac01\ud55c\ub2e4’\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n

IBD[https:\/\/pubmed.ncbi.nlm.nih.gov\/24833941\/<\/a>\u00a0]\ub294 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc(UC)\uacfc \ud06c\ub860\ubcd1(CD)\uc744 \ud3ec\ud568\ud55c \uc704\uc7a5\uad00 \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658\uc73c\ub85c \uc804 \uc138\uacc4\uc801\uc73c\ub85c \ub9ce\uc740 \uc778\uad6c\uac00 \uc553\uace0 \uc788\ub294\ub370 \ubbf8\uad6d\uc5d0\uc11c\ub9cc \uc131\uc778 2\ubc31\ub9cc \uba85\uc774 \uc99d\uc0c1\uc744 \uc553\uace0 \uc788\ub2e4. \uc774 \uc9c8\ud658\uc740 \uce58\ub8cc \ubd88\uac00\ud560 \ubfd0 \uc544\ub2c8\ub77c \ub300\uc7a5\uc554 \ubc1c\ubcd1\ub960\uc744 4\ubc30 \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \ud604\uc7ac IBD \uce58\ub8cc\ubc95\uc778 \ud56d\uc5fc\uc99d\uc81c\ub294 \uae0d\uc815\uc801\uc778 \uc608\ud734\uc640 \ubc00\uc811\ud55c \uc5f0\uad00\uc774 \uc788\ub294 \uc810\ub9c9 \uce58\uc720\ub97c \uc81c\ud55c\uc801\uc73c\ub85c \uac1c\uc120\ud558\ub294 \ud6a8\uacfc\ub9cc \uc788\uace0 \uc54c\ub824\uc838 \uc788\ub2e4.<\/p>\n

\uc5f0\uad6c\u00a0\uacb0\uacfc\uc5d0\u00a0\ub530\ub974\uba74\u00a0PHD\ub294\u00a0\uc7a5\ub0b4\u00a0\ubc29\uc5b4\ubcbd\u00a0\ubcf4\ud638\u00a0\uc720\uc804\uc790\uc758\u00a0\ubc1c\ud604\uc744\u00a0\uc720\ub3c4\ud558\ub294\u00a0\uc800\uc0b0\uc18c\uc99d\u00a0\uc720\ub3c4\uc778\uc790(HIF-1\u03b1)\uc758\u00a0\uc548\uc815\uc131\uacfc\u00a0\uc804\uc0ac\u00a0\ud65c\ub3d9\u00a0\uc870\uc808\uc5d0\u00a0\uc911\uc694\ud55c\u00a0\uc5ed\ud560\uc744\u00a0\ud55c\ub2e4. PHD\ub294\u00a0IBD \ud658\uc790\uc5d0\uc11c\u00a0\uc720\ud6a8\ud558\uac8c\u00a0\uc0c1\ud5a5\u00a0\uc870\uc808\ub418\uc5c8\uace0\u00a0\uc5fc\uc99d\uc131\u00a0\uc0ac\uc774\ud1a0\uce74\uc778\u00a0\ubc0f\u00a0\uc138\ud3ec\u00a0\uc0ac\uba78\u00a0\ub9c8\ucee4\uc758\u00a0\ubc1c\ud604\uacfc\u00a0\ub192\uc740\u00a0\uc0c1\uad00\uad00\uacc4\ub97c\u00a0\ubcf4\uc600\ub294\ub370, \uc774\ub294\u00a0IBD \uce58\ub8cc\uc5d0\u00a0PHD\ub97c\u00a0\uc7a0\uc7ac\ub825\uc744\u00a0\uac00\uc9c0\uace0\u00a0\uc788\ub2e4\ub294\u00a0\uac83\uc744\u00a0\uc758\ubbf8\ud55c\ub2e4.<\/p>\n

2022\ub144\u00a01\uc6d4\u00a0Insilico\ub294PHD\ub97c\u00a0\ud0c0\uac9f\ud55c\u00a0IBD \uce58\ub8cc\uc5d0\u00a0ISM5411\uc744\u00a0\uc804\uc784\uc0c1\u00a0\uc2e4\ud5d8\u00a0\ud6c4\ubcf4(PCC)\ub85c\u00a0\uc120\uc815\ud588\ub2e4. ISM5411\ub294\u00a0Insilico\uc758\u00a0\ubd84\uc790\u00a0\uac1c\ubc1c\uc744\u00a0\uc704\ud55c\u00a0\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc5d4\uc9c4\uc778\u00a0Chemistry42\ub97c\u00a0\uc0ac\uc6a9\ud558\uc5ec\u00a0\uac1c\ubc1c\ub410\uc73c\uba70\u00a0\uc0c8\ub85c\uc6b4\u00a0\uc2a4\uce90\ud3f4\ub4dc\uc640\u00a0\ud2b9\uc218\ud55c\u00a0\ubc14\uc778\ub529\u00a0\ubaa8\ub4dc\uac00\u00a0\ud2b9\uc9d5\uc774\ub2e4. \uc804\uc784\uc0c1\u00a0\ub2e8\uacc4\uc5d0\uc11c\u00a0ISM5411\ub294\u00a0\uacbd\uad6c\uc6a9\u00a0\uc7a5\ub0b4\u00a0\uc81c\ud55c\uc801\u00a0\uc800\ubd84\uc790\u00a0\uc5b5\uc81c\uc81c\ub85c\uc11c\u00a0\uc591\ud638\ud55c\u00a0\uc548\uc804\uc131\u00a0\uc815\ubcf4\uc640\u00a0\ud6a8\uacfc\uc801\uc778\u00a0\ud56d\ub300\uc7a5\uc5fc\u00a0\ud6a8\ub2a5\uc744\u00a0\uc785\uc99d\ud55c\u00a0\ubc14\u00a0\uc788\ub2e4.\u00a0<\/p>\n

Insilico\uc758\u00a0\uacf5\ub3d9\u00a0\ucd5c\uace0\uacbd\uc601\ucc45\uc784\uc790\uc774\uc790\u00a0\ucd5c\uace0\uacfc\ud559\ucc45\uc784\uc790\uc778\u00a0Feng Ren \ubc15\uc0ac\ub294\u00a0‘IBD\uc758\u00a0\ubc1c\ubcd1\ub960\uc758\u00a0\uc99d\uac00\ub294\u00a0\uc804\u00a0\uc138\uacc4\u00a0\uc758\ub8cc\u00a0\uc2dc\uc2a4\ud15c\uc5d0\u00a0\ud070\u00a0\ubd80\ub2f4\uc73c\ub85c\u00a0\uc791\uc6a9\ud55c\ub2e4’\uba70\u00a0‘\uc778\uacf5\uc9c0\ub2a5\uc774\u00a0\ub514\uc790\uc778\ud55c\u00a0ISM5411\uc740\u00a0\uc7a5\ub0b4\u00a0\ubc29\uc5b4\ubcbd\u00a0\ubcf4\ud638\u00a0\uac15\ud654\ub77c\ub294\u00a0\ub3c5\ud2b9\ud55c\u00a0\uba54\ucee4\ub2c8\uc998\uc73c\ub85c\u00a0\uc810\ub9c9\uc744\u00a0\uce58\uc720\ud558\ub3c4\ub85d\u00a0\uc124\uacc4\ub418\uc5c8\ub294\ub370\u00a0\uc774\ub294\u00a0IBD \ud658\uc790\uc758\u00a0\ud601\uc2e0\uc801\uc778\u00a0\uce58\ub8cc\u00a0\ubc29\uc2dd\uc73c\ub85c\u00a0\ucc44\ud0dd\ub420\u00a0\uc218\u00a0\uc788\ub294\u00a0\uc7a0\uc7ac\ub825\uc744\u00a0\uc9c0\ub2cc\ub2e4. ISM5411 \uc784\uc0c1\uc2e4\ud5d8\uc744\u00a0\ucd09\uc9c4\ud558\uc5ec\u00a0\uc784\uc0c1\uc758\u00a0\uc694\uad6c\uc0ac\ud56d\uc744\u00a0\ucda9\uc871\ud560\u00a0\uc218\u00a0\uc788\ub3c4\ub85d\u00a0\ucd5c\uc120\uc744\u00a0\ub2e4\ud558\uaca0\ub2e4’\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n

\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uae30\ubc18\uc758\u00a0Insilico\ub294\u00a0\uc778\uacf5\uc9c0\ub2a5\uacfc\u00a0\ucd5c\ucca8\ub2e8\u00a0\uae30\uc220\uc758\u00a0\uad50\ucc28\uc810\uc5d0\u00a0\uc11c\u00a0\uc788\ub2e4. \ub610\ud55c\u00a0\uc0dd\ubb3c\ud559, \ud654\ud559, \uadf8\ub9ac\uace0\u00a0\uc784\uc0c1\u00a0\uac1c\ubc1c\uc744\u00a0\ud55c\u00a0\ub370\u00a0\uc787\ub294\u00a0\ud1b5\ud569\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uae30\ubc18\u00a0\uc2e0\uc57d\u00a0\uac1c\ubc1c\u00a0\ud50c\ub7ab\ud3fc\uc778\u00a0Pharma.AI\ub97c\u00a0\ud65c\uc6a9\ud558\uc5ec\u00a030\uc5ec\uac1c\uc758\u00a0\ud30c\uc774\ud504\ub77c\uc778\uc744\u00a0\ubcf4\uc720\ud558\uace0\u00a0\uc788\uc73c\uba70\u00a0\uc774\u00a0\uc911\u00a05\uac1c\ub294\u00a0\uc784\uc0c1\u00a0\uc2e4\ud5d8\u00a0\ub2e8\uacc4\uc5d0\u00a0\uc788\ub2e4. \ucd5c\uadfc\u00a0Insilico\ub294\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc54c\uace0\ub9ac\uc998\u00a0\uc5f0\uad6c\uc640\u00a0\ud50c\ub7ab\ud3fc\u00a0\uac1c\ubc1c\u00a0\uc5ed\ub7c9\u00a0\uac15\ud654\ub97c\u00a0\uc704\ud574\u00a0\uce90\ub098\ub2e4\u00a0\ubaac\ud2b8\ub9ac\uc62c\uc5d0\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc5f0\uad6c\uac1c\ubc1c\u00a0\uc13c\ud130\ub97c\u00a0\ubc1c\uc871\ud588\ub2e4.<\/p>\n

Insilico\uc758\u00a0\ucc3d\ub9bd\uc790\uc774\uc790\u00a0\uacf5\ub3d9\u00a0\ucd5c\uace0\uacbd\uc601\ucc45\uc784\uc790\uc778\u00a0Alex Zhavoronkoy\ub294\u00a0‘\ub2f9\uc0ac\ub294\u00a0\uc778\uac04\uc758\u00a0\ub3c5\ucc3d\uc131\uacfc\u00a0\uacb0\ud569\ub41c\u00a0\ucd5c\ucca8\ub2e8\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uae30\uc220\uc744\u00a0\uc0ac\uc6a9\ud558\uc5ec\u00a0\ud658\uc790\ub97c\u00a0\ub3d5\uae30\u00a0\uc704\ud574\u00a0\ub178\ub825\ud558\uace0\u00a0\uc788\ub2e4’\uba70\u00a0‘\uc774\ubc88\u00a0IBD \ud504\ub85c\uadf8\ub7a8\uc740\u00a0\uc5b4\ub824\uc6b4\u00a0\uc9c8\ubcd1\uc5d0\u00a0\uc0c8\ub85c\uc6b4\u00a0\uce58\ub8cc\ubc95\uc744\u00a0\ub3c4\uc785\ud558\uae30\u00a0\uc704\ud574\u00a0\uc778\uacf5\uc9c0\ub2a5\u00a0\uc54c\uace0\ub9ac\uc998\uc744\u00a0\uc0ac\uc6a9\ud558\ub294\u00a0\ucd5c\uc2e0\u00a0\uc0ac\ub840\uc774\ub2e4’\ub77c\uace0\u00a0\ub9d0\ud588\ub2e4.<\/p>\n

Insilico Medicine \uc18c\uac1c<\/p>\n

\uae00\ub85c\ubc8c\u00a0\uc0dd\uc131\ud615\u00a0\uc778\uacf5\uc9c0\ub2a5(AI) \uae30\ubc18\u00a0\uc784\uc0c1\u00a0\ub2e8\uacc4\u00a0\uc0dd\uba85\uacf5\ud559\u00a0\uae30\uc5c5\uc778\u00a0Insilico Medicine\uc740\u00a0\ucc28\uc138\ub300\u00a0\uc778\uacf5\uc9c0\ub2a5\uc744\u00a0\ud65c\uc6a9\ud558\uc5ec\u00a0\uc0dd\ubb3c\ud559, \ud654\ud559, \uadf8\ub9ac\uace0\u00a0\uc784\uc0c1\u00a0\uc2e4\ud5d8\u00a0\ubd84\uc11d\uc744\u00a0\uacb0\ud569\ud55c\ub2e4. \uc774\u00a0\ud68c\uc0ac\ub294\u00a0\uc2e0\uaddc\u00a0\ud0c0\uae43\u00a0\ubc1c\uacac\uacfc\u00a0\uc6d0\ud558\ub294\u00a0\ud2b9\uc131\uc744\u00a0\uac00\uc9c4\u00a0\uc2e0\uaddc\u00a0\ubd84\uc790\u00a0\uad6c\uc870\u00a0\uc0dd\uc131\uc744\u00a0\uc704\ud574\u00a0\uc2ec\uce35\u00a0\uc0dd\uc131\u00a0\ubaa8\ub378, \uac15\ud654\u00a0\ud559\uc2b5, \ud2b8\ub79c\uc2a4\ud3ec\uba38\u00a0\ub4f1\uacfc\u00a0\uac19\uc740\u00a0\ud604\ub300\u00a0\uae30\uacc4\u00a0\ud559\uc2b5\u00a0\uae30\uc220\uc744\u00a0\uc0ac\uc6a9\ud558\ub294\u00a0\uc778\uacf5\u00a0\uc9c0\ub2a5\u00a0\ud50c\ub7ab\ud3fc\uc744\u00a0\uac1c\ubc1c\ud588\ub2e4. Insilico Medicine\uc740\u00a0\uc554, \uc12c\uc720\ud654, \uba74\uc5ed, \uc911\ucd94\uc2e0\uacbd\uacc4\u00a0\uc9c8\ud658, \uac10\uc5fc\uc131\u00a0\uc9c8\ud658, \uc790\uac00\uba74\uc5ed\u00a0\uc9c8\ud658, \ub178\ud654\u00a0\uad00\ub828\u00a0\uc9c8\ud658\u00a0\ub4f1\uc744\u00a0\uce58\ub8cc\ud558\uae30\u00a0\uc704\ud55c\u00a0\uc2e0\uc57d\uc744\u00a0\uac1c\ubc1c\ud558\ub294\u00a0\ud601\uc2e0\uc801\uc778\u00a0\uc194\ub8e8\uc158\uc744\u00a0\uac1c\ubc1c\ud558\ub294\u00a0\ub370\u00a0\uc9d1\uc911\ud55c\ub2e4.<\/p>\n

www.insilico.com<\/a><\/p>\n

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